RPS3 antibody

Catalog No. ABIN7118598

Product Details anti-RPS3 Antibody

Target: RPS3 (Ribosomal Protein S3 (RPS3))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This RPS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ribosomal protein S3

Clone: 5C7

Isotype: IgG1

Application Details

Application Notes: WB: 1:10000-1:50000, IP: 1:1000-1:2000, IHC: 1:50-1:200, IF: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for RPS3

Target: RPS3 (Ribosomal Protein S3 (RPS3))

Alternative Name: RPS3 (RPS3 Products)

Background: Synonyms:40S ribosomal protein S3, ribosomal protein S3, RPS3 Background:40S ribosomal protein S3 (RPS3), also named as SW-cl.26, is a 243 amino acid protein,which contains one KH type-2 domain and belongs to the ribosomal protein S3P family. RPS3 localizes in the cytoplasm. RPS3 is identified in a IGF2BP1-dependent mRNP granule complex, which contains untranslated mRNAs. RPS3 plays a role in repairing various DNA damage acting as a repair UV endonuclease. Nuclear accumulation of RPS3 results in an increase in DNA repair activity to some extent, thereby sustaining neuronal survival. The calculated molecular weight of RPS3 is 26 kDa, but the modified RPS3 is about 33 kDa.

Molecular Weight: 33 kDa

Gene ID: 6188

UniProt: P23396

Pathways: Positive Regulation of Endopeptidase Activity