Endoglin antibody (AA 58-110)

Catalog No. ABIN707561

Product Details anti-Endoglin Antibody

Target: Endoglin (ENG)

Binding Specificity: AA 58-110

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endoglin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD105

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Endoglin antibody (ABIN707561)

Bidkhori, Ahmadiankia, Matin, Heirani-Tabasi, Farshchian, Naderi-Meshkin, Shahriyari, Dastpak, Bahrami: "Chemically primed bone-marrow derived mesenchymal stem cells show enhanced expression of chemokine receptors contributed to their migration capability." in: Iranian journal of basic medical sciences, Vol. 19, Issue 1, pp. 14-9, (2016) (PubMed).

Wang, Emond, Flynn, Swaminathan, Kibbe: "Microparticle levels after arterial injury and NO therapy in diabetes." in: The Journal of surgical research, Vol. 200, Issue 2, pp. 722-31, (2015) (PubMed).

Gao, Zhang, Zhang, Zou, Liu: "Identification of rat respiratory mucosa stem cells and comparison of the early neural differentiation potential with the bone marrow mesenchymal stem cells in vitro." in: Cellular and molecular neurobiology, Vol. 34, Issue 2, pp. 257-68, (2014) (PubMed).

Gierloff, Nitsche, Adam-Klages, Liebs, Hedderich, Gassling, Wiltfang, Kabelitz, Açil: "In vitro comparison of different carrier materials with rat bone marrow MSCs." in: Clinical oral investigations, Vol. 18, Issue 1, pp. 247-59, (2014) (PubMed).

Zhao, Yin, Guo, Wang, Wang, Chen: "Placental expression of VEGF is increased in pregnancies with hydatidiform mole: possible association with developing very early onset preeclampsia." in: Early human development, Vol. 89, Issue 8, pp. 583-8, (2013) (PubMed).

Long, Qiu, Wang, Yang, Jia, Xin, Wang, Han, Fei, Liu: "Genetically engineered bone marrow mesenchymal stem cells improve functional outcome in a rat model of epilepsy." in: Brain research, Vol. 1532, pp. 1-13, (2013) (PubMed).

Wang, Long, Jia, Liu, Yi, Yang, Fei, Liu: "Over-expression of Mash1 improves the GABAergic differentiation of bone marrow mesenchymal stem cells in vitro." in: Brain research bulletin, Vol. 99, pp. 84-94, (2013) (PubMed).

Gao, Zhao, Song, Yang: "Expression pattern of embryonic stem cell markers in DFAT cells and ADSCs." in: Molecular biology reports, Vol. 39, Issue 5, pp. 5791-804, (2012) (PubMed).

Target Details for Endoglin

Target: Endoglin (ENG)

Alternative Name: CD105 (ENG Products)

Synonyms: ENG antibody, MGC137842 antibody, DKFZp469D0419 antibody, END antibody, HHT1 antibody, ORW1 antibody, AI528660 antibody, AI662476 antibody, CD105 antibody, S-endoglin antibody, endoglin antibody, ENG antibody, Eng antibody

Background:

Synonyms: END, HHT1, ORW1, Endoglin, CD15, ENG

Background: Major glycoprotein of vascular endothelium. Involved in the regulation of angiogenesis. May play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors. Acts as TGF-beta coreceptor and is involved in the TGF-beta/BMP signaling cascade. Required for GDF2/BMP9 signaling through SMAD1 in endothelial cells and modulates TGF-beta1 signaling through SMAD3.

Gene ID: 2022

UniProt: P17813