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ARHGEF18 antibody

ARHGEF18 Reactivity: Human, Mouse ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7118503
  • Target See all ARHGEF18 Antibodies
    ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
    Reactivity
    • 56
    • 4
    • 1
    Human, Mouse
    Host
    • 53
    • 2
    • 1
    Rabbit
    Clonality
    • 54
    • 2
    Polyclonal
    Conjugate
    • 16
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF18 antibody is un-conjugated
    Application
    • 31
    • 29
    • 13
    • 13
    • 8
    • 8
    • 5
    • 4
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    rho/rac guanine nucleotide exchange factor(GEF) 18
    Isotype
    IgG
    Top Product
    Discover our top product ARHGEF18 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
    Alternative Name
    ARHGEF18 (ARHGEF18 Products)
    Synonyms
    arhgef18 antibody, wu:fc21e04 antibody, wu:fj05f11 antibody, zgc:85686 antibody, P114-RhoGEF antibody, AI467246 antibody, D030053O22Rik antibody, rho/rac guanine nucleotide exchange factor (GEF) 18a antibody, Rho/Rac guanine nucleotide exchange factor (GEF) 18 antibody, Rho/Rac guanine nucleotide exchange factor 18 antibody, rho guanine nucleotide exchange factor 18 antibody, rho/rac guanine nucleotide exchange factor (GEF) 18 antibody, arhgef18a antibody, ARHGEF18 antibody, LOC100027283 antibody, Arhgef18 antibody
    Background
    Synonyms:KIAA0521 Background:Acts as guanine nucleotide exchange factor(GEF) for RhoA GTPases. Its activation induces formation of actin stress fibers. Also act as a GEF for RAC1, inducing production of reactive oxygen species(ROS). Does not act as a GEF for CDC42. The G protein beta-gamma(Gbetagamma) subunits of heterotrimeric G proteins act as activators, explaining the integrated effects of LPA and other G-protein coupled receptor agonists on actin stress fiber formation, cell shape change and ROS production. Required for EPB41L4B-mediated regulation of the circumferential actomyosin belt in epithelial cells(PubMed:22006950).
    Molecular Weight
    120-130 kDa
    Gene ID
    23370
    UniProt
    Q6ZSZ5
    Pathways
    Neurotrophin Signaling Pathway
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