Chc1 antibody, zgc:65796 antibody, zgc:77114 antibody, wu:fj77f08 antibody, rcc1 antibody, chc1-a antibody, BJ1 antibody, CG10480 antibody, CG18640 (Bj1) antibody, Dmel\\CG10480 antibody, RCC1 antibody, RanGEF antibody, Rcc1 antibody, dRCC1 antibody, inxs antibody, sdt antibody, xrcc1 antibody, chc1-b antibody, MGC115703 antibody, MGC132085 antibody, CHC1 antibody, RCC1-I antibody, SNHG3-RCC1 antibody, 4931417M11Rik antibody, AI326872 antibody, regulator of chromosome condensation 1 antibody, regulator of chromosome condensation 1 L homeolog antibody, Regulator of chromosome condensation 1 antibody, N terminal fragment of RCC1; similar to S. cerevisiae SRM1 (YGL097W) guanine nucleotide exchange factor for Gsp1 GTPase involved in assembly of nuclear pore complex; frameshifted antibody, regulator of chromosome condensation 1 S homeolog antibody, rcc1 antibody, RCC1 antibody, rcc1.L antibody, Rcc1 antibody, rcc1.S antibody
Background
Synonyms:CHC1 Background:Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex(together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.