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RRAGB antibody

RRAGB Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7118323
  • Target See all RRAGB Antibodies
    RRAGB (Ras-Related GTP Binding B (RRAGB))
    Reactivity
    • 26
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 4
    Rabbit
    Clonality
    • 25
    • 1
    Polyclonal
    Conjugate
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    This RRAGB antibody is un-conjugated
    Application
    • 23
    • 18
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    Ras-related GTP binding B
    Isotype
    IgG
    Top Product
    Discover our top product RRAGB Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    RRAGB (Ras-Related GTP Binding B (RRAGB))
    Alternative Name
    RRAGB (RRAGB Products)
    Synonyms
    RAGB antibody, bA465E19.1 antibody, Ragb antibody, RRAGB antibody, Ras related GTP binding B antibody, Ras-related GTP binding B antibody, RRAGB antibody, RragB antibody, Rragb antibody
    Background
    Synonyms: Background:Guanine nucleotide-binding protein that plays a crucial role in the cellular response to amino acid availability through regulation of the mTORC1 signaling cascade. Forms heterodimeric Rag complexes with RRAGC or RRAGD and cycles between an inactive GDP-bound and an active GTP-bound form. In its active form participates to the relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. Involved in the RCC1/Ran-GTPase pathway.
    Molecular Weight
    40 kDa
    Gene ID
    10325
    UniProt
    Q5VZM2
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