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RAD51D antibody

RAD51D Reactivity: Human, Rat, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7118256
  • Target See all RAD51D Antibodies
    RAD51D (RAD51 Homolog D (RAD51D))
    Reactivity
    • 28
    • 2
    • 2
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 23
    • 4
    • 1
    Rabbit
    Clonality
    • 25
    • 3
    Polyclonal
    Conjugate
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RAD51D antibody is un-conjugated
    Application
    • 19
    • 10
    • 5
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    RAD51-like 3(S. cerevisiae)
    Isotype
    IgG
    Top Product
    Discover our top product RAD51D Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    RAD51D (RAD51 Homolog D (RAD51D))
    Alternative Name
    Rad51D (RAD51D Products)
    Synonyms
    R51H3 antibody, Rad51l3 antibody, TRAD antibody, RAD51 paralog D antibody, Rad51d antibody
    Background
    Synonyms:RAD51L3 Background:Involved in the homologous recombination repair(HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA(ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM.
    Molecular Weight
    23-25 kDa
    Gene ID
    5892
    UniProt
    O75771
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