2900054P15Rik antibody, AW555448 antibody, C77700 antibody, RAB12, member RAS oncogene family antibody, RAB12 antibody, Rab12 antibody
Background
Synonyms:RAB12, Ras related protein Rab 12 Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy(By similarity).