RGD1308538 antibody, Rab11-FIP2 antibody, nRip11 antibody, 4930470G04Rik antibody, A830046J09Rik antibody, AW558126 antibody, Nrip11 antibody, RAB11 family interacting protein 2 antibody, RAB11 family interacting protein 2 (class I) antibody, Rab11fip2 antibody, RAB11FIP2 antibody
Background
Synonyms:KIAA0941 Background:A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate(PtdInsP3) and phosphatidic acid(PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment(ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.