POT1 antibody

Catalog No. ABIN7117924

Product Details anti-POT1 Antibody

Target: POT1 (Protection of Telomeres 1 (POT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: POT1 protection of telomeres 1 homolog (S. pombe)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Alternative Name: POT1 (POT1 Products)

Synonyms: HPOT1 antibody, POT1 antibody, DKFZp469P1825 antibody, pot1 antibody, 1500031H18Rik antibody, AI851169 antibody, Pot1 antibody, Pot1a antibody, protection of telomeres 1 antibody, protection of telomeres 1 L homeolog antibody, protection of telomeres 1A antibody, POT1 antibody, pot1.L antibody, Pot1a antibody, Pot1 antibody

Background: Synonyms: Background:This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

Molecular Weight: 75 kDa

Gene ID: 25913

UniProt: Q9NUX5

Pathways: Cell Division Cycle, Telomere Maintenance