PRSS50 antibody

Catalog No. ABIN7117876

Product Details anti-PRSS50 Antibody

Target: PRSS50 (Protease, serine, 50 (PRSS50))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS50 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: testes-specific protease 50

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PRSS50

Target: PRSS50 (Protease, serine, 50 (PRSS50))

Alternative Name: TSP50 (PRSS50 Products)

Synonyms: 79H19C antibody, Tsp50 antibody, CT20 antibody, TSP50 antibody, protease, serine 50 antibody, Prss50 antibody, PRSS50 antibody

Background: Synonyms:Cancer/testis antigen 20, CT20, PRSS50, Serine protease 50, testes protease 50, TSP50 Background:TSP50(Testis-specific protease-like protein 50) is also named as PRSS50, CT20 and belongs to the peptidase S1 family. It can enhance the expression of NFKB target genes involved in cell proliferation, and promotes cell proliferation, at least partially, through activation of the NFKB signalling pathway(PMID:21385156). There are two protein bands of 37 kDa and 43 kDa to be detected in human testes that the the difference is most likely caused by posttranslational proteolytic cleavage(PMID:11782390). The full length protein has a signal peptide with 39 amino acids and two glycosylation sites.

Molecular Weight: 50 kDa

Gene ID: 29122

UniProt: A0A140VJY3