PREB antibody

Catalog No. ABIN7117807

Product Details anti-PREB Antibody

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PREB antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: prolactin regulatory element binding

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PREB

Target: PREB (Prolactin Regulatory Element Binding (PREB))

Alternative Name: PREB (PREB Products)

Synonyms: C85705 antibody, SEC12 antibody, prolactin regulatory element binding antibody, PREB antibody, Preb antibody

Background: Synonyms:SEC12 Background:Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitement of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. Was first identified based on its probable role in the regulation of pituitary gene transcription. Binds to the prolactin gene(PRL) promoter and seems to activate transcription.

Molecular Weight: 45 kDa

Gene ID: 10113

UniProt: Q9HCU5

Pathways: ER-Nucleus Signaling