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POLR3K antibody

POLR3K Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7117684
  • Target See all POLR3K Antibodies
    POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
    Reactivity
    • 27
    • 8
    • 8
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 5
    Rabbit
    Clonality
    • 24
    • 3
    Polyclonal
    Conjugate
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This POLR3K antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    polymerase(RNA) III(DNA directed) polypeptide K, 12.3 kDa
    Isotype
    IgG
    Top Product
    Discover our top product POLR3K Primary Antibody
  • Application Notes
    WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    POLR3K (Polymerase (RNA) III (DNA Directed) Polypeptide K, 12.3 KDa (POLR3K))
    Alternative Name
    POLR3K (POLR3K Products)
    Synonyms
    MGC108467 antibody, POLR3K antibody, 12.3kDa antibody, 1500004O14Rik antibody, AI196849 antibody, AU014893 antibody, C11 antibody, RPC10 antibody, RPC11 antibody, C11-RNP3 antibody, RPC12.5 antibody, hRPC11 antibody, RNA polymerase III subunit K antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa S homeolog antibody, polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa antibody, polymerase (RNA) III (DNA directed) polypeptide K antibody, Polr3k antibody, polr3k.S antibody, polr3k antibody, POLR3K antibody
    Background
    Synonyms:C11, C11 RNP3, hRPC11, HsC11p, My010, POLR3K, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RPC10, RPC11, RPC12.5 Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity).
    Molecular Weight
    12 kDa
    Gene ID
    51728
    UniProt
    Q9Y2Y1
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