POLR2J antibody

Catalog No. ABIN7117677

This anti-POLR2J antibody is a Rabbit Polyclonal antibody detecting POLR2J in WB, ELISA and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for POLR2J antibody (ABIN7117677)

Target: POLR2J (Polymerase (RNA) II (DNA Directed) Polypeptide J, 13.3kDa (POLR2J))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR2J antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-POLR2J Antibody

Purpose: POLR2J antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: polymerase(RNA) II(DNA directed) polypeptide J, 13.3kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for POLR2J

Target: POLR2J (Polymerase (RNA) II (DNA Directed) Polypeptide J, 13.3kDa (POLR2J))

Alternative Name: POLR2J

Background:

Synonyms: DNA-directed RNA polymerase II subunit RPB11-a (RNA polymerase II subunit B11-a, RPB11a)|DNA-directed RNA polymerase II subunit J-1|RNA polymerase II 13.3 kDa subunit|POLR2J|POLR2J1

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft(By similarity).

Molecular Weight: 13 kDa

Gene ID: 5439

UniProt: P52435

Pathways: Regulatory RNA Pathways