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PHACTR4 antibody

PHACTR4 Reactivity: Human, Mouse, Rat WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7117389
  • Target See all PHACTR4 Antibodies
    PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))
    Reactivity
    • 23
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 23
    Rabbit
    Clonality
    • 22
    Polyclonal
    Conjugate
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    This PHACTR4 antibody is un-conjugated
    Application
    • 23
    • 19
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    phosphatase and actin regulator 4
    Isotype
    IgG
    Top Product
    Discover our top product PHACTR4 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    PHACTR4 (Phosphatase and Actin Regulator 4 (PHACTR4))
    Alternative Name
    PHACTR4 (PHACTR4 Products)
    Synonyms
    3110001B12Rik antibody, AI527228 antibody, AW495572 antibody, C330013F19Rik antibody, N28169 antibody, mKIAA4120 antibody, phactr4 antibody, zgc:63484 antibody, zgc:123224 antibody, phosphatase and actin regulator 4 antibody, phosphatase and actin regulator 4b antibody, phosphatase and actin regulator 4 L homeolog antibody, phosphatase and actin regulator 4 S homeolog antibody, phosphatase and actin regulator 4a antibody, Phactr4 antibody, phactr4b antibody, PHACTR4 antibody, phactr4.L antibody, phactr4.S antibody, Tsp_08786 antibody, phactr4 antibody, phactr4a antibody
    Background
    Synonyms: Background:Regulator of protein phosphatase 1(PP1) required for neural tube and optic fissure closure, and enteric neural crest cell(ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells(ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin(COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway(By similarity).
    Molecular Weight
    71-85 kDa
    Gene ID
    65979
    UniProt
    Q8IZ21
    Pathways
    Tube Formation
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