PHF2 antibody
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- Target See all PHF2 Antibodies
- PHF2 (PHD Finger Protein 2 (PHF2))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PHF2 antibody is un-conjugated
- Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- PHD finger protein 2
- Isotype
- IgG
- Top Product
- Discover our top product PHF2 Primary Antibody
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anti-PHD Finger Protein 2 (PHF2) (AA 936-985) antibody
PHF2 Reactivity: Human, Rabbit WB Host: Rabbit Polyclonal unconjugated
anti-PHD Finger Protein 2 (PHF2) (AA 2-100) antibodyPHF2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 3E7 unconjugated
anti-PHD Finger Protein 2 (PHF2) (Middle Region) antibodyPHF2 Reactivity: Human, Rabbit, Cow, Horse, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:200-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- PHF2 (PHD Finger Protein 2 (PHF2))
- Alternative Name
- PHF2 (PHF2 Products)
- Synonyms
- CENP-35 antibody, GRC5 antibody, JHDM1E antibody, im:4200679 antibody, phf8 antibody, wu:fa14c10 antibody, PHD finger protein 2 antibody, PHF2 antibody, Phf2 antibody, phf2 antibody
- Background
- Synonyms:GRC5, JHDM1E, KIAA0662, PHD finger protein 2, PHF2 Background:Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3(H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3(H3K4me3) at rDNA promoters and promotes expression of rDNA.
- Molecular Weight
- 100 kDa, 150 kDa
- Gene ID
- 5253
- UniProt
- O75151
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