PEX19 antibody

Catalog No. ABIN7117347

Product Details anti-PEX19 Antibody

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PEX19 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: peroxisomal biogenesis factor 19

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PEX19

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Alternative Name: PEX19 (PEX19 Products)

Synonyms: BEST:GH03076 antibody, CG5325 antibody, DmelPex19 antibody, Dmel\\CG5325 antibody, D1S2223E antibody, HK33 antibody, PBD12A antibody, PMP1 antibody, PMPI antibody, PXF antibody, PXMP1 antibody, Pxf antibody, PxF antibody, Peroxin-19 antibody, Peroxin 19 antibody, Peroxisomal farnesylated protein antibody, peroxisomal biogenesis factor 19 antibody, Pex19 antibody, Bm1_19905 antibody, PEX19 antibody

Background: Synonyms:33 kDa housekeeping protein, D1S2223E, HK33, Peroxin 19, PEX19, PMP1, PMPI, PXF, PXMP1 Background:This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Molecular Weight: 37 kDa

Gene ID: 5824

UniProt: P40855