PAPD5 antibody

Catalog No. ABIN7117222

Product Details anti-PAPD5 Antibody

Target: PAPD5 (PAP Associated Domain Containing 5 (PAPD5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPD5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: PAP associated domain containing 5

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PAPD5

Target: PAPD5 (PAP Associated Domain Containing 5 (PAPD5))

Alternative Name: PAPD5 (PAPD5 Products)

Synonyms: TRF4-2 antibody, LOC568678 antibody, 5730445M16Rik antibody, 5830428A09 antibody, poly(A) RNA polymerase D5, non-canonical antibody, PAP associated domain containing 5 antibody, PAP associated domain containing 5 L homeolog antibody, PAPD5 antibody, Papd5 antibody, papd5 antibody, CC1G_07969 antibody, papd5.L antibody

Background: Synonyms:PAPD5, Terminal uridylyltransferase 3, TRF4 2, TUTase 3 Background:Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity(in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion.

Molecular Weight: 50 kDa, 80 kDa

Gene ID: 64282

UniProt: Q8NDF8