OSBPL10 antibody

Catalog No. ABIN7117172

The Rabbit Polyclonal anti-OSBPL10 antibody has been validated for WB, ELISA, IHC, IP and IF. It is suitable to detect OSBPL10 in samples from Human, Rat and Mouse.

Quick Overview for OSBPL10 antibody (ABIN7117172)

Target: OSBPL10 (Oxysterol Binding Protein-Like 10 (OSBPL10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBPL10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-OSBPL10 Antibody

Purpose: OSBPL10 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: oxysterol binding protein-like 10

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for OSBPL10

Target: OSBPL10 (Oxysterol Binding Protein-Like 10 (OSBPL10))

Alternative Name: OSBPL10

Background:

Synonyms: Oxysterol-binding protein-related protein 10 (ORP-10, OSBP-related protein 10)|OSBPL10|ORP10|OSBP9

Background: Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate(PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P(PubMed:23934110)(Probable). Plays a role in negative regulation of lipid biosynthesis(PubMed:19554302). Negatively regulates APOB secretion from hepatocytes(PubMed:19554302, PubMed:22906437). Binds cholesterol and acidic phospholipids(PubMed:22906437). Also binds 25-hydroxycholesterol(PubMed:17428193). Binds phosphatidylserine(PubMed:23934110).

Molecular Weight: 75-80 kDa, 64 kDa

Gene ID: 114884

UniProt: Q9BXB5