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OTUD7B antibody

OTUD7B Reactivity: Human, Mouse, Rat WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7117156
  • Target See all OTUD7B Antibodies
    OTUD7B (OTU Domain Containing 7B (OTUD7B))
    Reactivity
    • 39
    • 13
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 4
    Rabbit
    Clonality
    • 37
    • 2
    Polyclonal
    Conjugate
    • 18
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This OTUD7B antibody is un-conjugated
    Application
    • 27
    • 20
    • 20
    • 4
    • 3
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    OTU domain containing 7B
    Isotype
    IgG
    Top Product
    Discover our top product OTUD7B Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    OTUD7B (OTU Domain Containing 7B (OTUD7B))
    Alternative Name
    OTUD7B (OTUD7B Products)
    Synonyms
    OTUD7B antibody, ZA20D1 antibody, za20d1 antibody, zgc:152772 antibody, cezanne antibody, CEZANNE antibody, 2900060B22Rik antibody, 4930463P07Rik antibody, AI462125 antibody, Trabid2 antibody, Za20d1 antibody, RGD1308111 antibody, OTU deubiquitinase 7B antibody, OTU domain containing 7B antibody, OTUD7B antibody, otud7b antibody, Otud7b antibody
    Background
    Synonyms:ZA20D1 Background:Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses. In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B. Negatively regulates mucosal immunity against infections. Mediates deubiquitination of EGFR. Has deubiquitinating activity toward 'Lys-11', 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. In vitro, has preference for 'Lys-11'-linked polyubiquitin chains, however such data are unsure in vivo. Hydrolyzes both linear and branched forms of polyubiquitin.
    Molecular Weight
    100 kDa
    Gene ID
    56957
    UniProt
    Q6GQQ9
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