OCRL antibody

Catalog No. ABIN7117103

Product Details anti-OCRL Antibody

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OCRL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: oculocerebrorenal syndrome of Lowe

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for OCRL

Target: OCRL (Oculocerebrorenal Syndrome of Lowe (OCRL))

Alternative Name: OCRL (OCRL Products)

Synonyms: OCRL antibody, wu:fi09g03 antibody, zgc:152864 antibody, locr antibody, nphl2 antibody, ocrl1 antibody, inpp5f antibody, INPP5F antibody, LOCR antibody, NPHL2 antibody, OCRL-1 antibody, OCRL1 antibody, 9530014D17Rik antibody, BB143339 antibody, OCRL, inositol polyphosphate-5-phosphatase antibody, phosphatidylinositol polyphosphate 5-phosphatase antibody, oculocerebrorenal syndrome of Lowe antibody, Ocrl antibody, NAEGRDRAFT_58601 antibody, OCRL antibody, ocrl antibody

Background: Synonyms:INPP5F, OCRL1 Background:Converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate. Also converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate(PubMed:25869668, PubMed:7761412, PubMed:9430698). May function in lysosomal membrane trafficking by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with lysosomes. Involved in primary cilia assembly(PubMed:22228094, PubMed:22543976).

Molecular Weight: 105 kDa

Gene ID: 4952

UniProt: Q01968

Pathways: Inositol Metabolic Process