NUP85 antibody

Catalog No. ABIN7117054

Product Details anti-NUP85 Antibody

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP85 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nucleoporin 85kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for NUP85

Target: NUP85 (Nucleoporin 85kDa (NUP85))

Alternative Name: NUP85 (NUP85 Products)

Synonyms: Pcnt1 antibody, frount antibody, pcnt1 antibody, zgc:100943 antibody, Nup75 antibody, nucleoporin 85kDa L homeolog antibody, nucleoporin 85kDa antibody, nucleoporin 85 antibody, nup85.L antibody, nup85 antibody, NUP85 antibody, Nup85 antibody

Background: Synonyms:NUP75, PCNT1 Background:Essential component of the nuclear pore complex(NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol 3-kinase-Rac-lammellipodium protrusion cascade.

Molecular Weight: 70-75kd

Gene ID: 79902

UniProt: Q9BW27