NLRX1 antibody

Catalog No. ABIN7116905

Product Details anti-NLRX1 Antibody

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NLR family member X1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:500, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for NLRX1

Target: NLRX1 (NLR Family Member X1 (NLRX1))

Alternative Name: NLRX1 (NLRX1 Products)

Synonyms: CLR11.3 antibody, DLNB26 antibody, NOD26 antibody, NOD5 antibody, NOD9 antibody, BC034204 antibody, RGD1311293 antibody, NLR family member X1 antibody, NLRX1 antibody, nlrx1 antibody, Nlrx1 antibody

Background: Synonyms:Caterpiller protein 11.3, CLR11.3, DLNB26, NLR family member X1, NLRX1, NOD26, NOD5, NOD9 Background:Participates in antiviral signaling. Acts as a negative regulator of MAVS-mediated antiviral responses, through the inhibition of the virus-induced RLH(RIG-like helicase)-MAVS interaction(PubMed:18200010). Has no inhibitory function on NF-Kappa-B and type 1 interferon signaling pathways, but enhances NF-Kappa-B and JUN N-terminal kinase dependent signaling through the production of reactive oxygen species(PubMed:18219313).

Molecular Weight: 110 kDa

Gene ID: 79671

UniProt: Q86UT6

Pathways: SARS-CoV-2 Protein Interactome