Neudesin antibody

Catalog No. ABIN7116786

Product Details anti-Neudesin Antibody

Target: Neudesin (NENF)

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Neudesin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: neuron derived neurotrophic factor

Clone: 7C8

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Neudesin

Target: Neudesin (NENF)

Alternative Name: NENF (NENF Products)

Synonyms: nenf antibody, CIR2 antibody, SCIRP10 antibody, SPUF antibody, Spuf antibody, 1110060M21Rik antibody, neudesin neurotrophic factor antibody, neuron derived neurotrophic factor antibody, nenf antibody, NENF antibody, Nenf antibody

Background: Synonyms:CIR2, NENF, NEUDESIN, SCIRP10, SPUF, SPUF protein Background:Acts as a neurotrophic factor in postnatal mature neurons enhancing neuronal survival. Promotes cell proliferation and neurogenesis in undifferentiated neural pro-genitor cells at the embryonic stage and inhibits differentiation of astrocyte. Its neurotrophic activity is exerted via MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT pathways. Neurotrophic activity is enhanced by binding to heme. Acts also as an anorexigenic neurotrophic factor that contributes to energy balance(By similarity). Plays a role in the human tumorigenesis(PubMed:22748190).

Molecular Weight: 18 kDa

Gene ID: 29937

UniProt: Q9UMX5