NPHP3 antibody

Catalog No. ABIN7116776

Product Details anti-NPHP3 Antibody

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nephronophthisis 3(adolescent)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for NPHP3

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Alternative Name: NPHP3 (NPHP3 Products)

Synonyms: si:dkey-56l10.1 antibody, MKS7 antibody, NPH3 antibody, RHPD antibody, 3632410F03Rik antibody, AI550417 antibody, C230078J01 antibody, D330020E01Rik antibody, pcy antibody, RGD1563856 antibody, nephronophthisis 3 antibody, nephrocystin 3 antibody, nephronophthisis 3 (adolescent) antibody, nphp3 antibody, NPHP3 antibody, Nphp3 antibody

Background: Synonyms:KIAA2000 Background:Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

Molecular Weight: 145-151 kDa

Gene ID: 27031

UniProt: Q7Z494

Pathways: cAMP Metabolic Process