NCK2 antibody

Catalog No. ABIN7116755

Product Details anti-NCK2 Antibody

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NCK adaptor protein 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for NCK2

Target: NCK2 (NCK Adaptor Protein 2 (NCK2))

Alternative Name: NCK2 (NCK2 Products)

Synonyms: GRB4 antibody, NCKbeta antibody, NCK2 antibody, 4833426I10Rik antibody, Grb4 antibody, Nck-2 antibody, Nck2 antibody, zgc:55283 antibody, fd20h08 antibody, im:7147817 antibody, si:ch211-147g19.3 antibody, wu:fd20h08 antibody, zgc:92024 antibody, NCK adaptor protein 2 antibody, cytoplasmic protein NCK2-like antibody, non-catalytic region of tyrosine kinase adaptor protein 2 antibody, NCK adaptor protein 2a antibody, NCK adaptor protein 2b antibody, NCK2 antibody, Nck2 antibody, LOC100227348 antibody, nck2a antibody, nck2b antibody

Background: Synonyms:GRB4 Background:This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 43 kDa

Gene ID: 8440

UniProt: O43639

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization