MAGEA6 antibody

Catalog No. ABIN7116158

Product Details anti-MAGEA6 Antibody

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: melanoma antigen family A, 6

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for MAGEA6

Target: MAGEA6 (Melanoma Antigen Family A, 6 (MAGEA6))

Alternative Name: MAGEA6 (MAGEA6 Products)

Synonyms: Mage-a6 antibody, CT1.6 antibody, MAGE-3b antibody, MAGE3B antibody, MAGE6 antibody, melanoma antigen, family A, 6 antibody, MAGE family member A6 antibody, Magea6 antibody, MAGEA6 antibody

Background: Synonyms:MAGE6 Background:Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme(E2) at the E3:substrate complex. May play a role in tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines.

Molecular Weight: 66-70 kDa

Gene ID: 4105

UniProt: P43360