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MAML1 antibody

MAML1 Reactivity: Human, Mouse, Rat ELISA, WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7116076
  • Target See all MAML1 Antibodies
    MAML1 (Mastermind-Like 1 (MAML1))
    Reactivity
    • 29
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 28
    • 1
    • 1
    Rabbit
    Clonality
    • 30
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This MAML1 antibody is un-conjugated
    Application
    • 24
    • 20
    • 13
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    mastermind-like 1(Drosophila)
    Isotype
    IgG
    Top Product
    Discover our top product MAML1 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    MAML1 (Mastermind-Like 1 (MAML1))
    Alternative Name
    MAML1 (MAML1 Products)
    Synonyms
    mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
    Background
    Synonyms:KIAA0200 Background:Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions.
    Molecular Weight
    108-120kd
    Gene ID
    9794
    UniProt
    Q92585
    Pathways
    Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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