LNX1 antibody

Catalog No. ABIN7115860

Product Details anti-LNX1 Antibody

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LNX1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ligand of numb-protein X 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for LNX1

Target: LNX1 (Ligand of Numb-Protein X 1 (LNX1))

Alternative Name: LNX1 (LNX1 Products)

Synonyms: LNX1 antibody, fj78f06 antibody, lnx antibody, si:dkey-12h2.1 antibody, wu:fj78f06 antibody, zgc:152906 antibody, Lnx antibody, LNX antibody, MPDZ antibody, PDZRN2 antibody, ligand of numb-protein X 1 antibody, LNX1 antibody, lnx1 antibody, Lnx1 antibody

Background: Synonyms:LNX, PDZRN2 Background:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65(By similarity). Isoform 2 provides an endocytic scaffold for IGSF5/JAM4.

Molecular Weight: 70 kDa

Gene ID: 84708

UniProt: Q8TBB1