LRWD1 antibody
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- Target See all LRWD1 Antibodies
- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LRWD1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- leucine-rich repeats and WD repeat domain containing 1
- Isotype
- IgG
- Top Product
- Discover our top product LRWD1 Primary Antibody
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anti-Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 1-30), (N-Term) antibody
LRWD1 Reactivity: Mouse WB, IHC (p) Host: Rabbit Polyclonal RB29538 unconjugated
anti-Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1) (AA 4-33), (N-Term) antibodyLRWD1 Reactivity: Mouse, Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- LRWD1 (Leucine-Rich Repeat and WD Repeat-Containing Protein 1 (LRWD1))
- Alternative Name
- LRWD1 (LRWD1 Products)
- Synonyms
- CENP-33 antibody, ORCA antibody, 1200011O22Rik antibody, AU042569 antibody, AW548074 antibody, Orca antibody, si:dkey-261j4.9 antibody, wu:fb78b03 antibody, wu:ft31b04 antibody, leucine rich repeats and WD repeat domain containing 1 antibody, leucine-rich repeats and WD repeat domain containing 1 antibody, microRNA 5090 antibody, leucine-rich repeats and WD repeat domain containing 1 L homeolog antibody, LRWD1 antibody, Lrwd1 antibody, lrwd1 antibody, MIR5090 antibody, lrwd1.L antibody
- Background
- Synonyms:CENP-33, ORCA Background:Required for G1/S transition. Recruits and stabilizes the origin recognition complex(ORC) onto chromatin during G1 to establish pre-replication complex(preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3 in a cooperative manner with DNA methylation. Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
- Molecular Weight
- 85 kDa
- Gene ID
- 222229
- UniProt
- Q9UFC0
- Pathways
- Chromatin Binding
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