IQCB1 antibody

Catalog No. ABIN7115509

Product Details anti-IQCB1 Antibody

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IQCB1 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: IQ motif containing B1

Isotype: IgG

Application Details

Application Notes: IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IQCB1

Target: IQCB1 (IQ Motif Containing B1 (IQCB1))

Alternative Name: NPHP5,IQCB1 (IQCB1 Products)

Synonyms: piq antibody, nphp5 antibody, slsn5 antibody, MGC81507 antibody, IQCB1 antibody, zgc:101792 antibody, MGC146213 antibody, 6820449I09Rik antibody, AV128382 antibody, NPHP5 antibody, PIQ antibody, SLSN5 antibody, IQ motif containing B1 antibody, IQ motif containing B1 L homeolog antibody, IQ calmodulin-binding motif containing 1 antibody, Iqcb1 antibody, iqcb1.L antibody, IQCB1 antibody, iqcb1 antibody

Background: Synonyms:IQ motif containing B1, IQCB1, KIAA0036, Nephrocystin 5, NPHP5, PIQ, SLSN5 Background:IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.

UniProt: Q15051