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IFT57 antibody
IFT57
Reactivity: Human, Mouse, Rat
WB, IHC, ELISA, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-IFT57 Antibody
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Target
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IFT57
(Intraflagellar Transport 57 Homolog (IFT57))
Reactivity
All reactivities for IFT57 antibodies
Human, Mouse, Rat
Host
All hosts for IFT57 antibodies
Rabbit
Clonality
All clonalities for IFT57 antibodies
Polyclonal
Conjugate
All conjugates for IFT57 antibodies
This IFT57 antibody is un-conjugated
Application
All applications for IFT57 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
intraflagellar transport 57 homolog(Chlamydomonas)
Isotype
IgG
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Application Details
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Application Notes
WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for IFT57
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Target
IFT57
(Intraflagellar Transport 57 Homolog (IFT57))
Alternative Name
IFT57 (IFT57 Products )
Background
Synonyms:DERP8, ESRRBL1, HIPPI Background:Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway(By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8(CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator, however the relevance of such function remains unclear.
Molecular Weight
49kd
Gene ID
55081
UniProt
Q9NWB7
Pathways
Hedgehog Signaling , Positive Regulation of Endopeptidase Activity
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