IL-37 antibody

Catalog No. ABIN7115463

Product Details anti-IL-37 Antibody

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-37 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: interleukin 1 family, member 7(zeta)

Clone: 6A2

Isotype: IgG1

Application Details

Application Notes: WB: 1:1000-1:10000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IL-37

Target: IL-37 (IL37) (Interleukin 37 (IL37))

Alternative Name: IL37 (IL37 Products)

Synonyms: FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, interleukin 37 antibody, IL37 antibody

Background: Synonyms:FIL1Z, IL1F7, IL1H4, IL1RP1 Background:Suppressor of innate inflammatory and immune responses involved in curbing excessive inflammation. This function requires SMAD3. Suppresses, or reduces, proinflammatory cytokine production, including IL1A and IL6, as well as CCL12, CSF1, CSF2, CXCL13, IL1B, IL23A and IL1RN, but spares anti-inflammatory cytokines. Inhibits dendritic cell activation.

Molecular Weight: 30 kDa

Gene ID: 27178

UniProt: Q9NZH6