INO80 antibody

Catalog No. ABIN7115249

Product Details anti-INO80 Antibody

Target: INO80 (INO80 Homolog (INO80))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This INO80 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: INO80 homolog(S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for INO80

Target: INO80 (INO80 Homolog (INO80))

Alternative Name: INO80 (INO80 Products)

Synonyms: ATINO80 antibody, INO80 ORTHOLOG antibody, INO80 ortholog antibody, INO80A antibody, INOC1 antibody, hINO80 antibody, Inoc1 antibody, RGD1310969 antibody, 2310079N15Rik antibody, 4632409L19Rik antibody, DNA helicase INO80-like protein antibody, INO80 complex subunit antibody, INO80 antibody, Ino80 antibody

Background: Synonyms:INO80A, INOC1, KIAA1259 Background:DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair, according to PubMed:20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double-stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segregation during normal cell division cycle.

Molecular Weight: 177,150 kDa

Gene ID: 54617

UniProt: Q9ULG1

Pathways: Positive Regulation of Response to DNA Damage Stimulus