IVNS1ABP antibody

Catalog No. ABIN7115224

Product Details anti-IVNS1ABP Antibody

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IVNS1ABP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: influenza virus NS1A binding protein

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for IVNS1ABP

Target: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Alternative Name: IVNS1ABP (IVNS1ABP Products)

Target Type: Influenza Protein

Background: Synonyms:ARA3, FLARA3, KIAA0850, NS1, NS1BP Background:Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines(By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Molecular Weight: 70 kDa

Gene ID: 10625

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling