HOOK3 antibody

Catalog No. ABIN7115107

Product Details anti-HOOK3 Antibody

Target: HOOK3 (Hook Homolog 3 (HOOK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOOK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: hook homolog 3(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for HOOK3

Target: HOOK3 (Hook Homolog 3 (HOOK3))

Alternative Name: HOOK3 (HOOK3 Products)

Synonyms: 5830454D03Rik antibody, AI317159 antibody, E330005F07Rik antibody, HK3 antibody, hook3 antibody, hook microtubule-tethering protein 3 antibody, hook microtubule tethering protein 3 antibody, hook microtubule-tethering protein 3 L homeolog antibody, Hook3 antibody, HOOK3 antibody, hook3.L antibody

Background: Synonyms: Background:Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking(By similarity). Component of the FTS/Hook/FHIP complex(FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex(the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex.

Molecular Weight: 83 kDa

Gene ID: 84376

UniProt: Q86VS8

Pathways: Stem Cell Maintenance, Maintenance of Protein Location