GADD45GIP1 antibody

Catalog No. ABIN7114772

Product Details anti-GADD45GIP1 Antibody

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GADD45GIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: growth arrest and DNA-damage-inducible, gamma interacting protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for GADD45GIP1

Target: GADD45GIP1 (Growth Arrest and DNA-Damage-Inducible, gamma Interacting Protein 1 (GADD45GIP1))

Alternative Name: GADD45GIP1 (GADD45GIP1 Products)

Synonyms: si:dkey-194e13.6 antibody, CKBBP2 antibody, CRIF1 antibody, PLINP antibody, PLINP-1 antibody, PRG6 antibody, Plinp1 antibody, 2310040G17Rik antibody, AI425883 antibody, Crif1 antibody, growth arrest and DNA-damage-inducible, gamma interacting protein 1 antibody, GADD45G interacting protein 1 antibody, gadd45gip1 antibody, GADD45GIP1 antibody, Gadd45gip1 antibody

Background: Synonyms:MRPL59, PLINP1, PRG6 Background:Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis.

Molecular Weight: 25-28kd

Gene ID: 90480

UniProt: Q8TAE8