GAN antibody

Catalog No. ABIN7114555

Product Details anti-GAN Antibody

Target: GAN (Gigaxonin (GAN))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAN antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: gigaxonin

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for GAN

Target: GAN (Gigaxonin (GAN))

Alternative Name: GAN (GAN Products)

Synonyms: MGC81691 antibody, GAN antibody, A330045G18 antibody, gigaxonin antibody, GAN1 antibody, KLHL16 antibody, gigaxonin L homeolog antibody, gigaxonin antibody, giant axonal neuropathy antibody, gan.L antibody, gan antibody, GAN antibody, Gan antibody

Background: Synonyms:GAN1, KLHL16 Background:Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.

Molecular Weight: 68kd

UniProt: Q9H2C0