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GEMIN8 antibody

GEMIN8 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7114530
  • Target See all GEMIN8 Antibodies
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Reactivity
    • 30
    • 9
    • 8
    Human
    Host
    • 28
    • 2
    Rabbit
    Clonality
    • 28
    • 2
    Polyclonal
    Conjugate
    • 9
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GEMIN8 antibody is un-conjugated
    Application
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    gem(nuclear organelle) associated protein 8
    Isotype
    IgG
    Top Product
    Discover our top product GEMIN8 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    GEMIN8 (Gem (Nuclear Organelle) Associated Protein 8 (GEMIN8))
    Alternative Name
    GEMIN8 (GEMIN8 Products)
    Synonyms
    FAM51A1 antibody, B130034M20Rik antibody, B930082C09Rik antibody, BC023488 antibody, gemin-8 antibody, gem nuclear organelle associated protein 8 antibody, gemin8 antibody, GEMIN8 antibody, Gemin8 antibody
    Background
    Synonyms:FAM51A1 Background:The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins(snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. Dissociation by the SMN complex of CLNS1A from the trapped Sm proteins and their transfer to an SMN-Sm complex triggers the assembly of core snRNPs and their transport to the nucleus.
    Molecular Weight
    32 kDa
    Gene ID
    54960
    UniProt
    Q9NWZ8
    Pathways
    Ribonucleoprotein Complex Subunit Organization
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