FERMT3 antibody

Catalog No. ABIN7114179

This anti-FERMT3 antibody is a Rabbit Polyclonal antibody detecting FERMT3 in WB, ELISA, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for FERMT3 antibody (ABIN7114179)

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FERMT3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FERMT3 Antibody

Purpose: FERMT3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: fermitin family homolog 3(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FERMT3

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Alternative Name: FERMT3

Background:

Synonyms: Fermitin family homolog 3|Kindlin-3|MIG2-like protein|Unc-112-related protein 2|FERMT3|KIND3|MIG2B|URP2

Background: Plays a central role in cell adhesion in hematopoietic cells(PubMed:19234463, PubMed:26359933). Acts by activating the integrin beta-1-3(ITGB1, ITGB2 and ITGB3)(By similarity). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells(PubMed:19234460). Required for activation of integrin beta-2(ITGB2) in polymorphonuclear granulocytes(PMNs)(By similarity). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis.

Molecular Weight: 72-76 kDa

Gene ID: 83706

UniProt: Q86UX7