FBXL15 antibody

Catalog No. ABIN7114035

Product Details anti-FBXL15 Antibody

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXL15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: F-box and leucine-rich repeat protein 15

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for FBXL15

Target: FBXL15 (F-Box and Leucine-Rich Repeat Protein 15 (FBXL15))

Alternative Name: FBXL15 (FBXL15 Products)

Background: Synonyms:FBXO37 Background:Substrate recognition component of a SCF(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of SMURF1, thereby acting as a positive regulator of the BMP signaling pathway. Required for dorsal/ventral pattern formation and bone mass maintenance. Also mediates ubiquitination of SMURF2 and WWP2.

Molecular Weight: 33 kDa

Gene ID: 79176

UniProt: Q9H469