EXD1 antibody
EXD1
Reactivity: Human, Rat, Mouse
WB, IF, ELISA, IHC
Host: Rabbit
Polyclonal
unconjugated
-
- Target See all EXD1 Antibodies
- EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))
- Reactivity
- Human, Rat, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This EXD1 antibody is un-conjugated
- Application
- Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- exonuclease 3'-5' domain containing 1
- Isotype
- IgG
-
-
- Application Notes
- WB: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
-
- Target
- EXD1 (Exonuclease 3'-5' Domain Containing 1 (EXD1))
- Alternative Name
- EXD1 (EXD1 Products)
- Synonyms
- EXDL1 antibody, Exdl1 antibody, RGD1561009 antibody, 4932702D22Rik antibody, exd1 antibody, exonuclease 3'-5' domain containing 1 antibody, EXD1 antibody, Exd1 antibody, exd1 antibody
- Background
- Synonyms:EXDL1 Background:RNA-binding component of the PET complex, a multiprotein complex required for the processing of piRNAs during spermatogenesis. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposable elements, preventing their mobilization, which is essential for the germline integrity(By similarity). The PET complex is required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs. In the PET complex, EXD1 probably acts as an RNA adapter. EXD1 is an inactive exonuclease(By similarity).
- Molecular Weight
- 36 kDa
- Gene ID
- 161829
- UniProt
- Q8NHP7
-
You are here:
