EIF3D antibody

Catalog No. ABIN7113954

Product Details anti-EIF3D Antibody

Target: EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This EIF3D antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: eukaryotic translation initiation factor 3, subunit D

Clone: 2D11

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for EIF3D

Target: EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))

Alternative Name: EIF3D (EIF3D Products)

Synonyms: eif3s7 antibody, eIF3d antibody, DDBDRAFT_0217568 antibody, DDBDRAFT_0219927 antibody, DDB_0217568 antibody, DDB_0219927 antibody, EIF3S7 antibody, An15g03780 antibody, AO090026000811 antibody, eIF3-p66 antibody, eIF3-zeta antibody, 66/67kDa antibody, AA407891 antibody, Eif3s7 antibody, eIF3p66 antibody, wu:fb12a03 antibody, zgc:64097 antibody, eukaryotic translation initiation factor 3 subunit D antibody, eukaryotic translation initiation factor 3 subunit 7 antibody, eukaryotic initiation factor antibody, eIF-3 zeta antibody, eukaryotic translation initiation factor 3, subunit D antibody, translation initiation factor eIF-3 subunit 7 antibody, eukaryotic translation initiation factor 3 subunit D S homeolog antibody, Eukaryotic translation initiation factor 3 subunit D antibody, eif3d antibody, EIF3D antibody, eIF3-S7 antibody, ANI_1_540134 antibody, AOR_1_1456014 antibody, PTRG_07832 antibody, VDBG_06053 antibody, PGTG_10613 antibody, Tsp_00484 antibody, Eif3d antibody, eif3d.S antibody, eif-3.D antibody

Background: Synonyms:EIF3S7 Background:Component of the eukaryotic translation initiation factor 3(eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex(43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2(PubMed:18056426).

Molecular Weight: 66 kDa

Gene ID: 8664

UniProt: O15371

Pathways: Ribonucleoprotein Complex Subunit Organization