CED-12 antibody, CED12 antibody, ELMO-2 antibody, ELMO2 antibody, MGC114811 antibody, 1190002F24Rik antibody, mKIAA1834 antibody, engulfment and cell motility 2 antibody, engulfment and cell motility protein 2 antibody, engulfment and cell motility 2 L homeolog antibody, ELMO2 antibody, LOC100232489 antibody, Elmo2 antibody, elmo2.L antibody, elmo2 antibody
Background
Synonyms:CED12A, KIAA1834 Background:Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor(GEF) activity of DOCK1.