DYNC1I2 antibody

Catalog No. ABIN7113667

This Rabbit Polyclonal antibody specifically detects DYNC1I2 in WB, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DYNC1I2 antibody (ABIN7113667)

Target: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DYNC1I2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-DYNC1I2 Antibody

Purpose: DYNC1I2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: dynein, cytoplasmic 1, intermediate chain 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DYNC1I2

Target: DYNC1I2 (Dynein, Cytoplasmic 1, Intermediate Chain 2 (DYNC1I2))

Alternative Name: DYNC1I2

Background:

Synonyms: Cytoplasmic dynein 1 intermediate chain 2|Cytoplasmic dynein intermediate chain 2|Dynein intermediate chain 2, cytosolic (DH IC-2)|DYNC1I2|DNCI2|DNCIC2

Background: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component(p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.

Molecular Weight: 68 kDa and 72 kDa

Gene ID: 1781

UniProt: Q13409

Pathways: M Phase