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DOC2B antibody

DOC2B Reactivity: Human, Rat, Mouse ELISA, WB, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7113615
  • Target See all DOC2B Antibodies
    DOC2B (Double C2-Like Domains, beta (DOC2B))
    Reactivity
    • 18
    • 5
    • 5
    • 1
    Human, Rat, Mouse
    Host
    • 17
    • 2
    Rabbit
    Clonality
    • 19
    Polyclonal
    Conjugate
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DOC2B antibody is un-conjugated
    Application
    • 9
    • 6
    • 6
    • 3
    • 2
    ELISA, Western Blotting (WB), Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    double C2-like domains, beta
    Isotype
    IgG
    Top Product
    Discover our top product DOC2B Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IF: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    DOC2B (Double C2-Like Domains, beta (DOC2B))
    Alternative Name
    DOC2B (DOC2B Products)
    Synonyms
    DOC2BL antibody, multiple C2 and transmembrane domain-containing protein 1-like antibody, double C2 domain beta antibody, double C2-like domains, beta antibody, double C2, beta antibody, LOC100369196 antibody, DOC2B antibody, doc2b antibody, Doc2b antibody
    Background
    Synonyms:DOC2BL Background:Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes(By similarity).
    Molecular Weight
    46kd
    Gene ID
    8447
    UniProt
    Q14184
    Pathways
    Positive Regulation of Peptide Hormone Secretion
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