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DOC2B antibody
DOC2B
Reactivity: Human, Rat, Mouse
ELISA, WB, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-DOC2B Antibody
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Target
See all DOC2B Antibodies
DOC2B
(Double C2-Like Domains, beta (DOC2B))
Reactivity
All reactivities for DOC2B antibodies
Human, Rat, Mouse
Host
All hosts for DOC2B antibodies
Rabbit
Clonality
All clonalities for DOC2B antibodies
Polyclonal
Conjugate
All conjugates for DOC2B antibodies
This DOC2B antibody is un-conjugated
Application
All applications for DOC2B antibodies
ELISA, Western Blotting (WB), Immunofluorescence (IF)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
double C2-like domains, beta
Isotype
IgG
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Discover our top product DOC2B Primary Antibody
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Application Details
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Application Notes
WB: 1:500-1:2000, IF: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for DOC2B
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Target
DOC2B
(Double C2-Like Domains, beta (DOC2B))
Alternative Name
DOC2B (DOC2B Products )
Synonyms
DOC2BL antibody, multiple C2 and transmembrane domain-containing protein 1-like antibody, double C2 domain beta antibody, double C2-like domains, beta antibody, double C2, beta antibody, LOC100369196 antibody, DOC2B antibody, doc2b antibody, Doc2b antibody
Background
Synonyms:DOC2BL Background:Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes(By similarity).
Molecular Weight
46kd
Gene ID
8447
UniProt
Q14184
Pathways
Positive Regulation of Peptide Hormone Secretion
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