DLC1 antibody

Catalog No. ABIN7113404

Product Details anti-DLC1 Antibody

Target: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: deleted in liver cancer 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for DLC1

Target: DLC1 (Deleted in Liver Cancer 1 (DLC1))

Alternative Name: DLC1 (DLC1 Products)

Background: Synonyms:ARHGAP7, KIAA1723, STARD12 Background:This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.

Molecular Weight: 171 kDa

Gene ID: 10395

UniProt: Q96QB1

Pathways: Tube Formation, Positive Regulation of Endopeptidase Activity