DACH2 antibody
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- Target See all DACH2 Antibodies
- DACH2 (Dachshund 2 (DACH2))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DACH2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- dachshund homolog 2(Drosophila)
- Isotype
- IgG
- Top Product
- Discover our top product DACH2 Primary Antibody
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- Application Notes
- WB: 1:500-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- DACH2 (Dachshund 2 (DACH2))
- Alternative Name
- DACH2 (DACH2 Products)
- Synonyms
- 9430028N04Rik antibody, RGD1561687 antibody, dachshund family transcription factor 2 antibody, dachshund 2 (Drosophila) antibody, dachshund family transcription factor 2 L homeolog antibody, dachshund homolog 2 antibody, dachshund homolog 2 (Drosophila) antibody, DACH2 antibody, Dach2 antibody, dach2.L antibody, LOC612847 antibody, dach2 antibody
- Background
- Synonyms: Background:Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by the overlying ectoderm, and DACH2 and PAX3 positively regulate each other's expression(By similarity). Probably binds to DNA via its DACHbox-N domain.
- Molecular Weight
- 65 kDa
- Gene ID
- 117154
- UniProt
- Q96NX9
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