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CPEB1 antibody

CPEB1 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7113294
  • Target See all CPEB1 Antibodies
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    Reactivity
    Human, Mouse, Rat
    Host
    • 45
    • 2
    • 1
    Rabbit
    Clonality
    • 48
    Polyclonal
    Conjugate
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPEB1 antibody is un-conjugated
    Application
    • 43
    • 24
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    cytoplasmic polyadenylation element binding protein 1
    Isotype
    IgG
    Top Product
    Discover our top product CPEB1 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    CPEB1 (Cytoplasmic Polyadenylation Element Binding Protein 1 (CPEB1))
    Alternative Name
    CPEB1 (CPEB1 Products)
    Synonyms
    CEBP antibody, CPE-BP1 antibody, CPEB antibody, AU024112 antibody, Cpeb antibody, mCPEB antibody, CPEB1 antibody, cpeb1 antibody, ZOR-1 antibody, cepb1b antibody, fd15c06 antibody, wu:fd15c06 antibody, zorba antibody, cytoplasmic polyadenylation element binding protein 1 antibody, hypothetical protein antibody, cytoplasmic polyadenylation element binding protein 1 L homeolog antibody, cytoplasmic polyadenylation element binding protein 1b antibody, cytoplasmic polyadenylation element binding protein 1 S homeolog antibody, CPEB1 antibody, Cpeb1 antibody, cpeb1 antibody, LOAG_17395 antibody, cpeb1.L antibody, cpeb1b antibody, cpeb1.S antibody
    Background
    Synonyms:CPEB Background:Sequence-specific RNA-binding protein that regulates mRNA cytoplasmic polyadenylation and translation initiation during oocyte maturation, early development and at postsynapse sites of neurons. Binds to the cytoplasmic polyadenylation element(CPE), an uridine-rich sequence element(consensus sequence 5'-UUUUUAU-3') within the mRNA 3'-UTR. In absence of phosphorylation and in association with TACC3 is also involved as a repressor of translation of CPE-containing mRNA, a repression that is relieved by phosphorylation or degradation(By similarity). Involved in the transport of CPE-containing mRNA to dendrites, those mRNAs may be transported to dendrites in a translationally dormant form and translationally activated at synapses(By similarity). Its interaction with APLP1 promotes local CPE-containing mRNA polyadenylation and translation activation(By similarity). Induces the assembly of stress granules in the absence of stress.
    Molecular Weight
    54 kDa
    Gene ID
    64506
    UniProt
    Q9BZB8
    Pathways
    Synaptic Membrane
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