Col10 antibody, Col10a-1 antibody, collagen, type X, alpha 1 antibody, collagen type X alpha 1 chain antibody, Col10a1 antibody, COL10A1 antibody
Background
Synonyms:COL10A1, collagen alpha-1(X) chain Background:This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).