COPE antibody

Catalog No. ABIN7112910

Product Details anti-COPE Antibody

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COPE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: coatomer protein complex, subunit epsilon

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for COPE

Target: COPE (Coatomer Protein Complex, Subunit epsilon (COPE))

Alternative Name: COPE (COPE Products)

Synonyms: COPE antibody, DDBDRAFT_0189670 antibody, DDBDRAFT_0233799 antibody, DDB_0189670 antibody, DDB_0233799 antibody, DKFZp469K1716 antibody, MGC80063 antibody, MGC130714 antibody, epsilon-COP antibody, 1110005D17Rik antibody, Cope1 antibody, coatomer protein complex subunit epsilon antibody, coatomer protein complex epsilon subunit antibody, coatomer protein complex subunit epsilon S homeolog antibody, coatomer protein complex, subunit epsilon antibody, COPE antibody, copE antibody, cope.S antibody, cope antibody, Cope antibody

Background: Synonyms: Background:The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors(ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors(By similarity).

Molecular Weight: 36 kDa

Gene ID: 11316

UniProt: O14579